Bioanalytical services for biopharmaceuticals
LGC’s industry leading bioanalytical centre in Cambridge (Fordham), UK, is recognised for leadership in science and technology.
Our Immunogenicity Centre of Excellence is built upon a wealth of experience in the development and validation of sensitive, specific, selective and drug tolerant assays to measure anti-drug antibody (ADA) responses to therapeutic protein products.
We have comprehensive capabilities for PK, immunogenicity and biomarkers that span LC-MS/MS through to immunoassay, cell and molecular biology.
Protein LC-MS – Mass spectrometry for the quantification of proteins
Our pioneering application of mass spectrometry based methodologies for the quantitation of biologicals gave rise to LGC’s Protein LC-MS Centre of Excellence.
Protein LC-MS provides a complementary technique to enzyme-linked immunosorbent assays (ELISA) enabling both top-down (analysis of intact proteins) and bottom-up (analysis of proteolytically cleaved fragments) approaches.
We understand the specific challenges of biopharmaceutical development and have a dedicated team of experts with a strong track record of solving difficult method development challenges.